Abstract
Background: Advances in cancer treatment have produced a growing population living with cancer as a chronic condition, shifting attention toward the psychosocial dimensions of the illness. Loneliness — the subjective distress arising from a perceived deficit in one's social relationships — is associated with symptom burden, psychological morbidity, and mortality, yet remains under-examined in Indian oncology settings, where family-centred caregiving norms are often assumed to be protective.
Objective: To assess the level of loneliness among cancer patients and its association with selected demographic and clinical variables.
Methods: A descriptive cross-sectional study was conducted among 200 cancer patients recruited consecutively from the oncology department of a tertiary care teaching hospital in Greater Noida, Uttar Pradesh, India. Loneliness was measured using the UCLA Loneliness Scale, Version 3, administered by structured interview alongside a sociodemographic and clinical proforma. Data were analysed using descriptive statistics and the chi-square test, with p < 0.05 considered significant.
Results: No participant scored in the low range. High loneliness was reported by 119 patients (59.5%) and moderate loneliness by 80 (40.0%), with one participant (0.5%) in the severe band; every participant therefore experienced at least moderate loneliness. Loneliness was significantly associated with age (p < 0.001), marital status (p = 0.014), religion (p < 0.001), and place of residence (p < 0.001), but not with gender, monthly income, smoking history, or treatment modality.
Conclusion: Loneliness was near-universal in this sample despite most patients being married and living within family households, indicating that the presence of family does not ensure emotional connectedness. Routine screening for loneliness should be embedded in oncology nursing assessment.
References
Adams, R. N., Mosher, C. E., Winger, J. G., Abonour, R., & Kroenke, K. (2018). Cancer-related loneliness mediates the relationships between social constraints and symptoms among cancer patients. Journal of Behavioral Medicine, 41(2), 243–252. https://doi.org/10.1007/s10865-017-9892-5
Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024). Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 74(3), 229–263. https://doi.org/10.3322/caac.21834
Deckx, L., van den Akker, M., & Buntinx, F. (2014). Risk factors for loneliness in patients with cancer: A systematic literature review and meta-analysis. European Journal of Oncology Nursing, 18(5), 466–477. https://doi.org/10.1016/j.ejon.2014.05.002
Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://doi.org/10.1007/s12160-010-9210-8
Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352
Jaremka, L. M., Fagundes, C. P., Glaser, R., Bennett, J. M., Malarkey, W. B., & Kiecolt-Glaser, J. K. (2013). Loneliness predicts pain, depression, and fatigue: Understanding the role of immune dysregulation. Psychoneuroendocrinology, 38(8), 1310–1317.
Okten, C., & Ozer, Z. (2016). Cancer patients and loneliness: A systematic review. Nursing Practice Today, 3(4), 128–139.
Perlman, D., & Peplau, L. A. (1981). Toward a social psychology of loneliness. In S. Duck & R. Gilmour (Eds.), Personal relationships: 3. Personal relationships in disorder (pp. 31–56). Academic Press.
Raque-Bogdan, T. L., Lamphere, B., Kostiuk, M., Gissen, M., & Beranek, M. (2019). Unpacking the layers: A meta-ethnography of cancer survivors' loneliness. Journal of Cancer Survivorship, 13(1), 21–33.
Rosedale, M. (2009). Survivor loneliness of women following breast cancer. Oncology Nursing Forum, 36(2), 175–183.
Şahin, Z. A., & Tan, M. (2012). Loneliness, depression, and social support of patients with cancer and their caregivers. Clinical Journal of Oncology Nursing, 16(2), 145–149.
Smith, S., Lally, P., Steptoe, A., Chavez-Ugalde, Y., Beeken, R. J., & Fisher, A. (2024). Prevalence of loneliness and associations with health behaviours and body mass index in 5835 people living with and beyond cancer: A cross-sectional study. BMC Public Health, 24. https://doi.org/10.1186/s12889-024-17797-3
Wheldon, C. W., Shahsavar, Y., Choudhury, A., McCormick, B. P., & Albertorio-Díaz, J. R. (2025). Loneliness among adult cancer survivors in the United States: Prevalence and correlates. Scientific Reports, 15(1), Article 3914. https://doi.org/10.1038/s41598-025-85126-8
World Health Organization. (2025). From loneliness to social connection: Charting a path to healthier societies. https://www.who.int/groups/commission-on-social-connection

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